A Comparative clinical observation was made on 112 cases of cirrhosis of the liver who were hospitalized and treated at the Kwangju Christian-Hospital in part 6 ´years. The diagnosis was confirmed and subclassified histopathologically according to needle biopsy findings.
The results are summarized as follows:
1. Of 112 cases, 89 cases (80%) were post necrotic, 8 cases (7%) were portal cirrhosis´ and remaining 15 cases (13%) were secondary biliary cirrhosis.
2. Sex incidence; Over all sex incidence was 6.3 to 1 in favor of male sex. The male to female sex ratio in post necrotic cirrhosis, portal cirrhosis, and biliary cirrhosis were 8.5 to 1, 3 to l and 14 to 1, respectively.
3. Age incidence; 86% of the´ cases were in their 4th to 7th decade and there was no difference am-ong subclasses of the disease.
4. Excess ethanol consumption, nutritional deficiency and past history suggesting hepatitis, all contributed as an etiologic factor in each subclass. 5. The main symptoms were fatigue, indigestion, abdominal pain and anorexia. In the portal cirrho*is, fatigue, and indigestion were prominent. In the biliary cirrhosis abdominal pa n was .ore prominent than the other symptoms
6. On physical examination´ hepatoi egaly was the most` frequent´ finding in :11 types of the cirrhosis. The rest of the physic. I finding, were com
mon mon to all types, except for the´ jau.dice which was more prominent in the cas, s of bilia y cirrhosis.
7. On Liver function test:
a. Of 78 cases studied, total serum b lirubin was elevated in 47 cases 60.7%). In biliar, cirrhosis, all the cases showed above 2m~g% and in 78% of the cases above 10mg in this specific type.
b. Elevated B.S.P. retention´ in 93.8´- of cases.
c. Serum total protein was diminishes in 12% of cases. A/G ratio was inverted in 61.: % of cases studied.
d. Prothrombin time was prolonged n 31.5% of cases.
e. Alkaline phosphatase war elevate in 92.5% and this finding was common in all ypes -of the cirrhosis.
f. SGOT. was elevated in about 80% of cases and there was no significant different among the histopathologic types. SGPT was, elevated in about 60% of the cases and again there was .o significant difference among the types.
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